The performances transcend the film's tropes, grounding it in characters that feel more complete than this subgenre often produces.

This is one of the few movies I've ever seen where the whole audience broke into spontaneous, loud applause a third of the way in.

This is a gorgeous movie made by a gorgeous spirit.

It is an exhilarating, distressing, funny and profound film, with one of the more memorable film scores in years,

Dr. Carrie Ross (Jessalyn Gilsig) is an entomologist on vacation with her daughter. They board a plane in Barranquilla, Columbia on the way to Miami. In the air, a passenger dies with bullet ants crawling out. Sky Marshal Ethan Hart (Antonio Sabato Jr.) takes charge with Ross's help. The ants start eating into the machinery and the plane is refused landing permission.This came one year after the superior camp "Snakes on a Plane". My guess is that this was rushed into production to take advantage. The difference is that this isn't funny, or at least not intentionally funny. The story is kinda stupid in a million different ways. I hesitate to see anything with Antonio Sabato Jr. I do like Jessalyn Gilsig but she can't save this flight. It's on a crash course and Samuel L. Jackson is not coming to the rescue.

Ran across this cliché ridden number on Lifetime of all places. It's story line and general focus lend itself more to SYFY but on either channel this was a sad dud. The BUGABOO this time are MUTANT ANTS being carried by a terribly ill passenger who seizures on an aircraft on it's way to Miami from an unnamed Central or South American country. The poor bastard who seizures and crashes to the floor of the aircraft cabin, vomits, then grotesque mutant nasty ants burst right of said sick passengers stomach ala "Alien" From 1937's "Five Came Back" with Lucille Ball to the "original" Classic 1954's "High and the Mighty" with the"Duke" all the way through the 5 (or was it 6?)airport movies, it's always fun to see how people and aircraft technology hold up in drama and/or comedy. For comedy just think Karen Black in "Airport 1975" when incredulous passengers (and most audiences) were known to murmur and yell "the stewardess is flying the plane!" Right........ Most of those films were entertaining and some were quite good.So now we come to "Destination Infestation".Catchy title that...don't you think? LOL. Clearly a close clone of "Snakes on a Plane", but far worse. Why worse? Ah, let me count the ways. Terrible acting, HUGE plot holes, ridiculous story elements and I could go on. However, there are many other films to see and review that are (hopefully) a better waste of time for me in my senior years. I will, however give you two examples of the insipidly stupid mistakes in this film. When calling Miami to divert their landing, it appears there is only ONE controller (maybe two, but you never see him/her)in the control tower. For a major city to have such a situation is ridiculous, particularly when an outside view of said tower show 5 small Cessna type aircraft and of all things MOUNTAINS IN THE DISTANCE Miami....I think not!The second plot hole (among a dozen at least), is just downright amusing. When Miami, Cuba and Haiti turn the aircraft down for landing the old pilot, mysteriously restored after being well bitten by the mutant ants then sprayed with foam from a fire extinguisher suddenly is back in the pilots seat. Oh where to land? DUH! When a mysterious "black ops" group closes all US air space for fear of the mutant ants.It sure looks like this plane is in a pickle.To the rescue the co-pilot remembers a short "closed and abandoned" US military runway in Alabama. So they fly on through US air space. No Planes or rockets bring them down and "Lo and Behold"!!!! As the A-Bus with it's 40 passengers approaches this supposed abandoned airfield...My goodness, the fields landing lights are on! What a coincidence? LOL!There are so many other absurdities in this film it would take another 5000 words to help you understand this is a truly pathetic attempt at fine entertainment, let alone a fine cinematic experience. I only schlepped through it because I love the "disaster in the air genre". If you do decide to waste two hrs, for a laugh, pay close attention to the woman who is sitting next to the lady who has a baby. You know in disaster films if your on an airplane and there is turbulence or aircraft trouble the passengers bounce around, the camera shakes and there is lots of vibration. Watch the lady with the pageboy black haircut seated on the aisle seat on the right hand side next to the woman passenger with the baby. She was told by the director, I'm sure, to "bounce" around in your seat at the appropriate times......LOL! She bounces and bounces, higher and higher! She stops bouncing only after everyone else and starts before every other passenger starts bouncing. I swear this lady bounces about 2 FEET straight up. She looks like she's having a great time and she's quite funny to watch!I give "DESINF" air tragedy a 2 out of 10. Eschew this crap and rent the "High and the Mighty", that is a GREAT air disaster film.

This movie is stupid in countless ways, but I'll focus on only one. The killer ant-infested plane was flying at 35,000 feet, where it is very cold. Insects are cold-blooded animals and cannot function effectively below room temperature. Whatever threat the ants presented could have been easily neutralized (at the penalty of some passenger discomfort) by turning off the heat in the aircraft and if necessary, ventilating in outside air. Evidently the basic physiology of insects never occurred to the writers, because early in the story the ants flee to the luggage hold, where they would instantly have been immobilized by the cold.This may not matter to disaster movie fans who love stereotypical disaster movie plots and characters, but folks who desire a modicum of believability will be disappointed to say the least.

Why do they even try and make these kind of movies? I turned this movie on expecting a cheesy, stupid movie about killer ants-it was even worse. The acting was atrocious, these people were incredibly unrealistic, and I simply hated the movie altogether.I turned it off halfway through because of the astonishing awfulness of this movie simply stunned me. It wasn't suspenseful, or scary, or dramatic, it's hardly even a film at all. It rates up there with 'Absolute Zero' as one of the worst TV movies I've ever seen (which is horrible--I've seen A LOT of bad TV movies).I like Jessalyn Gilsig in 'Heroes', and she was another reason I decided to turn this on. Even she was horrible. I didn't expect much from Antonio Sabato, Jr., as many fans of the sci-fi channel will understand.So, a 1/10. I can't stand the thought of watching another movie like this again. Ugh. *Starts puking*0/4